Irving L Weissman Selected Research

Non-Hodgkin Lymphoma (Lymphosarcoma)

11/2018	CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Lymphoma.
1/2015	Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential.
11/2011	Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy.
12/2010	Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47.
9/2010	Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Irving L Weissman Research Topics

Disease

67	Neoplasms (Cancer) 01/2022 - 07/2003
8	Leukemia 06/2012 - 02/2003
7	Neoplasm Metastasis (Metastasis) 01/2019 - 02/2011
6	Infections 01/2022 - 12/2002
5	Lymphoma (Lymphomas) 01/2020 - 06/2009
5	Melanoma (Melanoma, Malignant) 01/2020 - 05/2008
5	Urinary Bladder Neoplasms (Bladder Cancer) 01/2019 - 08/2009
5	Non-Hodgkin Lymphoma (Lymphosarcoma) 11/2018 - 09/2010
5	Teratoma (Teratoid Tumor) 01/2017 - 02/2006
4	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2012
4	Atherosclerosis 01/2020 - 01/2009
4	Inflammation (Inflammations) 01/2020 - 02/2011
4	Hypoxia (Hypoxemia) 11/2018 - 02/2014
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2015 - 12/2003
3	Fibrosis (Cirrhosis) 02/2022 - 01/2017
3	Graft vs Host Disease (Graft-Versus-Host Disease) 12/2013 - 07/2003
2	Neuroblastoma 01/2022 - 12/2010
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 01/2017
2	Wounds and Injuries (Trauma) 01/2021 - 10/2017
2	Brain Neoplasms (Brain Tumor) 12/2020 - 01/2017
2	Glioma (Gliomas) 12/2020 - 01/2017
2	Atherosclerotic Plaque (Atheroma) 01/2020 - 01/2020
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 04/2009
2	Body Weight (Weight, Body) 11/2018 - 01/2018
2	Medulloblastoma 10/2018 - 01/2017
2	Carcinogenesis 01/2018 - 03/2005
2	Hypertrophy 01/2018 - 01/2017
2	Colorectal Neoplasms (Colorectal Cancer) 01/2018 - 01/2017
2	Glioblastoma (Glioblastoma Multiforme) 02/2017 - 01/2017
2	Disease Progression 01/2016 - 02/2013
2	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 06/2013 - 02/2013
2	Circulating Neoplastic Cells 01/2012 - 11/2011
2	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 11/2011 - 10/2009
2	Blast Crisis (Blast Phase) 03/2009 - 08/2004
1	Cicatrix (Scar) 02/2022
1	Breakthrough Infections 01/2022
1	COVID-19 01/2022
1	Cytokine Release Syndrome 01/2022
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2021
1	Lewis Lung Carcinoma 01/2021

Drug/Important Bio-Agent (IBA)

24	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2003
20	AntibodiesIBA 01/2022 - 09/2010
19	Monoclonal AntibodiesIBA 01/2022 - 09/2010
8	AntigensIBA 01/2021 - 07/2010
7	Transcription Factors (Transcription Factor)IBA 11/2020 - 05/2007
6	CytokinesIBA 01/2022 - 04/2015
6	LigandsIBA 01/2022 - 01/2009
5	magrolimabIBA 01/2021 - 01/2015
4	CalreticulinIBA 01/2022 - 12/2010
4	beta CateninIBA 08/2009 - 08/2004
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2018
3	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021 - 04/2016
3	Rituximab (Mabthera)FDA Link 01/2021 - 09/2010
3	Complement System Proteins (Complement)IBA 01/2020 - 12/2013
3	ChemokinesIBA 01/2020 - 01/2009
3	Immune Checkpoint InhibitorsIBA 11/2018 - 11/2016
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017 - 05/2008
3	Imatinib Mesylate (Gleevec)FDA Link 06/2013 - 08/2004
3	Phosphotransferases (Kinase)IBA 02/2011 - 03/2009
2	HydrogelsIBA 02/2022 - 10/2017
2	Messenger RNA (mRNA)IBA 01/2022 - 04/2012
2	Immunoglobulin G (IgG)IBA 01/2022 - 02/2017
2	Peptides (Polypeptides)IBA 01/2021 - 05/2008
2	Epidermal Growth Factor (EGF)IBA 01/2021 - 12/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 04/2009
2	EnzymesIBA 01/2021 - 09/2009
2	Fc Receptors (Fc Receptor)IBA 01/2020 - 09/2010
2	Oxygen (Dioxygen)IBA 01/2018 - 04/2009
2	Adapalene (Differin)FDA LinkGeneric 01/2016 - 07/2010
2	MicroRNAs (MicroRNA)IBA 10/2015 - 03/2010
2	matrigelIBA 02/2014 - 05/2008
2	Biological ProductsIBA 10/2007 - 12/2006
2	Ganciclovir (Cytovene)FDA LinkGeneric 01/2007 - 02/2006
1	PolymersIBA 02/2022
1	AlkaliesIBA 02/2022
1	COVID-19 VaccinesIBA 01/2022
1	Secretory ComponentIBA 01/2022
1	Immunoglobulin A (IgA)IBA 01/2022
1	VaccinesIBA 01/2022
1	Myosin Light Chains (Myosin Essential Light Chain)IBA 01/2021
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2021
1	EpitopesIBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	ML 7IBA 01/2021
1	Trastuzumab (Herceptin)FDA Link 01/2021
1	epidermal growth factor receptor VIIIIBA 12/2020
1	Semaphorin-3AIBA 12/2020

Therapy/Procedure

31	Therapeutics 02/2022 - 04/2006
21	Immunotherapy 01/2020 - 04/2012
11	Transplantation 01/2017 - 12/2002
5	Cell Transplantation 10/2016 - 07/2003
4	Drug Therapy (Chemotherapy) 01/2021 - 06/2007
4	Heterologous Transplantation (Xenotransplantation) 01/2014 - 01/2012
3	Radiotherapy 01/2017 - 01/2005
3	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2016 - 08/2008
2	Ligation 01/2022 - 06/2014
2	Hepatectomy 01/2018 - 01/2017
2	Surgical Amputation (Amputations) 01/2018 - 01/2017
2	Hematopoietic Stem Cell Transplantation 07/2003 - 12/2002
1	Transjugular Intrahepatic Portasystemic Shunt 09/2021